Short is the new long. Twitter keeps you to 140 characters, which means sometimes you have to cut things short. Help make sense of the acronyms with the Abbreviations API (our our Abbreviations API profile). Pass a term and receive its many meanings, along with the context where each meaning is used.
Above are the default results when searching for ASAP. To hone in on the results you need, you can search by category. Perhaps help your users make sense of short content by automatically looking up a series of three or more uppercase letters? You can sort by popularity (here's the ASAP example) to find the abbreviation most likely to be a match.