The service provides a continuously curated repository of reference sources related to raw protein and genetic interactions. The search function indexes over 35,000 separate articles and other publications documenting over 550,000 raw protein and genetic interactions. Search provides free access to all interaction data for either immediate display or download.
API methods support submission of a search request specifying a single gene or a set of genes to retrieve a list of publications. For a single gene, publications reflect any interactions with other genes. Where multiple genes are specified, publications are returned only where they address those particular interactions. Search requests can also specify sources from which publication references are desired.
The BioGRID API is a RESTful API using XML and HTML to access over 35,000 articles that document over 550,000 raw protein and genetic interactions. The API webpage gives 9 examples of interactions returned as results, including for the human MDM2 gene and between S. cerevisiae CDC27, APC1 and APC2.