The service provides a RESTful interface to RENATO (REgulatory Network Analysis TOol) which provides network-based analysis to identify regulatory elements common to a list of genes. It is intended for interpretation and visualization of information about gene regulation by mapping genes submitted to the regulatory network and extracting connections. It also highlights over-representation of specific regulatory connections among genes in the list.
API methods support submission of a list of genes with parameters to specify regulatory connections of interest. Methods generate data showing transcriptional and post-transcriptional regulatory connections and highlighting regulatory links common among genes within the specified list.