From the website: "With E*TRADE's open XML-based Application Programming Interface, you can now use industry-leading trading applications to execute your trades directly through E*TRADE - no additional software needed." The API is REST based with OAuth for authentication model.
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The E*TRADE tutorial to develop applications in Java explains how to authorize with OAuth and retrieve a list of accounts. With the aim to enhance learning, E*TRADE also offers REST API reference, SDK documentation, and code snippets. Developer resources available at https://developer.etrade.com/ctnt/dev-portal