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The GA4GH WES API describes how a user can submit workflow requests to workflow execution systems in standardized ways. Workflow execution engines support this API so that users can make workflow requests programmatically. The Workflow Execution Schema is supported by multiple execution engines with the options of processing the same workflow across different workflow execution platforms running across various environments. It allows you to generate a JSON parameterization file, and submit this to a GA4GH compliant workflow execution service. Some features includes; the ability to request a workflow run using CWL or WDL, the ability to parameterize that workflow using a JSON schema, the ability to get information about running workflows, status, errors, output file locations and more. The Global Alliance for Genomics and Health is an international coalition, formed to enable the sharing of genomic and clinical data.