The ProDom blastProDom API provides a blast (blastn or blastp) on the ProDom database. Developers can enter a sequence, and the API will return blast output with the names of the families corresponding to the hits found along with a URL to get an image visualizing the blasted domains on the protein. The sequences submitted by developers may be nucleotides or proteins, raw or fasta format.
ProDom hosts a comprehensive database of protein domain families. These domain families are automatically generated from global comparisons of all available protein sequences in the UniProt Knowledge Database.