SEGUID is a protein sequence identifier based on the Secure Hash Algorithm (SHA-1) digest of the primary sequence. This protein identification system was created in response to changing and disappearing protein identifiers, a common problem in the bioinformatics community. A SEGUID is stable for the lifetime of a protein, because everyone can derive the same SEGUID from the sequence information. This allows easier data sharing between databases and research groups.
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So far, we don't have a record of any changes to this API