pyLast is a wrapper that provides a simple public interface to the Last.fm API, including support for scrobbling. The wrapper provides proxy support and is Python 3 friendly. pyLast has no dependencies aside from Python.
BandPage creates a platform where musicians, fans and others in the music industry can interact easily. For musicians, it can be difficult to stay connected to fans who are scattered all over the web. BandPage aims to rectify this issue by providing musicians with a one-stop-shop solution; update once and publish everywhere. Bands simply create a BandPage profile and all their info is updated across various other online channels as well. The BandPage API allows third party developers to access this data and integrate it into other applications.
ProgrammableWeb lists many popular Music APIs in the directory including Last.fm, 7digital and Spotify Metadata. This post features a few really creative, entertaining mashups that use a few popular Music APIs.