twython is an actively managed python wrapper for the Twitter and Twitter Streaming APIs. All functions are mapped to the coinciding endpoint in the Twitter docs, providing developers with a lot of flexibility.
The Votizen API aims to get friends to involve their friends in supporting candidates. The API website notes that the API is entirely based on HTTP. Votizen is based on the premise that, "Voters are more likely to listen to friends than campaign volunteers." Votizen is the first "social campaigning platform built entirely on personal connections."