The Linode Perl SDK by Linode can access the API to implement cloud hosting features. Modules cover a Perl interface with account, domain, and configuration methods.
If you're a developer hosting your apps on MediaTemple, then you'll want to get into the beta of the new MediaTemple API. Though you need to apply to get access, the company has provided quite a bit of information to drool over while you await for your API application to be approved.
One gap in Google's Cloud Platform had to do with the performance and cost of bandwidth hungry apps. Now, Google is partnering with CDNs to offer better options for developers.