At the time of this writing, there are 197 APIs listed in the Education Category of the ProgrammableWeb API Directory. A few of the leading APIs in this category include Khan Academy, Edmodo and Schoology.
There have been hundreds of Startup Weekends around the world in 2011 alone. By the end of the year, Seattle will have hosted several, including the Startup Weekend Seattle EDU which starts this weekend. The 54 hour event brings together software developers, graphic designers and business people to build education focused applications. What better way to give these new startups a leg up than to encourage them to build on top of one or more of the 40 education APIs in the directory?